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CPC mouthwashes reduce SARS-CoV-2 infectivity 1,000-fold

Laboratory studies certify this fact

CPC mouthwashes reduce SARS-CoV-2 infectivity 1,000-fold

A study highlights the importance of the mouth as a source of infection and transmission of SARS-CoV2, and it is essential to focus on oral health care to prevent the transmission of COVID-19 since the preclinical study carried out on cells cultured in the laboratory has demonstrated the antiviral effect of certain mouthwashes containing cetylpyridinium chloride (CPC), a molecule present in some oral antiseptics.

Specifically, CPC is capable of reducing up to 1,000-fold the infectivity of SARS CoV-2 in laboratory cell cultures.
At the present time, it would be very interesting to be able to offer the general population oral hygiene resources that, in addition to their known positive effects on oral health, could reduce the viral load and thus provide possible protection against the risk of transmission of the virus causing COVID-19.

CPC demonstrated antiviral effect.


 The results of this study conducted in the bioRxiv laboratory, in which CPC has been shown to have a clear antiviral role, allow the research team to move forward and conduct an efficacy trial in humans to study whether the use of CPC mouthwashes will help control microorganisms in the oral cavity. This allows the research team to move forward and conduct an efficacy trial in humans to study whether the use of mouthwashes with CPC will help control microorganisms in the oral cavity and reduce oral pathogens. Considering that in the experiment we have used a higher amount of virus than that found in the oral cavity of infected people, these results are very encouraging.

The next step is to know the results of the efficacy trial in humans, which has already begun, where we will be able to see if the molecule reduces the viral load in the saliva of people infected with SARS-CoV-2.

The mouth is a route of entry and transmission of microorganisms, which can multiply and produce infections in situ and systemically.

That is why the experts have insisted on the need for good oral hygiene because it can help to prevent the development of infectious pathologies, such as COVID-19. In this sense, they emphasize the importance of good oral health as a preventive measure and point to the need to include it in the package of basic preventive measures currently recommended.

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